Martin Jung

The paper identifies a conserved hydrophobic interaction that mediates competition between GPCR transducers and regulators.

The paper identifies PEX38 as a novel, essential peroxin in Euglenozoa, evolved from a remnant GET-pathway factor, and highlights its role in peroxisomal membrane protein targeting and potential as a therapeutic target.

The paper investigates how Mga2 converts membrane physical cues into biochemical outputs via ubiquitylation, revealing a signal amplification mechanism involving E3 ligase autoubiquitylation.

The paper identifies a dual-domain mechanism in the Flower protein that coordinates extracellular vesicle-mediated fitness selection and cell-intrinsic survival in astrocytes, with implications for Alzheimer's disease.

The paper classifies mitochondrial presequences into seven groups and identifies group A presequences as enhancing import efficiency through a specific targeting mechanism involving TOMM34.

This study characterizes Tgl2, a putative TAG lipase in yeast mitochondria, showing its dimerization, catalytic residues, and role in mitochondrial lipid homeostasis.

This study identifies Sbh1/Sec61β as a specific signal peptide receptor that recognizes and guides substrates into the Sec61 channel through its cytosolic IDR and conserved regions.

The paper characterizes the epigenomic organization of the Paramecium macronuclear genome, revealing broad histone mark domains and unique transcriptional features.

The paper investigates the role of two Piwi proteins in transgene-induced silencing in Paramecium, showing they have distinct but overlapping functions in generating and processing siRNAs for chromatin-level gene silencing.

This study identifies a spliced variant of STIM1, Stim1A, which alters its localization and function in SOCE, adapting Ca2+ entry to specific cellular contexts.