Sivarajan Karunanithi

The paper identifies brain-specific functions of NDD-associated genes by analyzing gene expression and regulatory mechanisms across tissues.

The paper identifies piRNAs from Y-chromosome gene families that regulate autosomal gene expression in mouse testis through homology to gene UTRs and genomic regions.

This study uses retinal organoids from USH1C patients to show disrupted Muller glia signaling leads to retinal degeneration and loss of integrity.

The paper characterizes the epigenomic organization of the Paramecium macronuclear genome, revealing broad histone mark domains and unique transcriptional features.

The paper investigates the role of two Piwi proteins in transgene-induced silencing in Paramecium, showing they have distinct but overlapping functions in generating and processing siRNAs for chromatin-level gene silencing.

RAPID automates siRNA analysis by generating visualizations and reports, enabling comparison of datasets and differential expression analysis.

The paper identifies a piRNA cluster on the mouse Y chromosome and shows that transcripts from multicopy gene families encode both piRNAs and proteins.