Molecular BiologyAmerican Journal of Physiology-Endocrinology and MetabolismPeer-reviewed
Islet macrophages drive islet remodeling and compensatory hyperinsulinemia in the early diabetes
Manesh Chittezhath, Divya Gunaseelan, Xiaofeng Zheng…·Yusuf Ali
The paper shows that islet resident macrophages drive islet remodeling and hyperinsulinemia in early type-2 diabetes by promoting vascularization and insulin secretion.