Tatsuya Kin

This study benchmarks porcine pancreatic ductal organoids (PPDO) against human pancreatic ductal organoids (HPDO) and primary porcine pancreas using scRNA-Seq, showing PPDO's potential for drug screening with conserved toxicity profiles.

The paper examines islet isolation and culture outcomes at the Alberta Diabetes Institute IsletCore, finding islet loss occurs within 24 hours of isolation with no further loss after extended culture.