BiochemistrybioRxivPreprint
Linoleic acid metabolite, 13-S-hydroxyoctadecadienoic acid, suppresses cancer cell growth by inhibiting mTOR
Seung Ju Park, Hongmok Kwon, A Yeong Yang…·Seyun Kim
The paper identifies 13-S-HODE as a tumor suppressive metabolite that inhibits mTOR by binding its ATP-binding domain, thereby suppressing cancer cell growth.