Matthew J. Dufort

B cell alpha(v) integrin regulates tissue specialization and clonal expansion of lung germinal center and memory B cells after viral infection.

This study shows that B cell v integrin limits GC activity and memory B cell expansion in the lung after IAV infection, suggesting it as a target for improving mucosal vaccines.

Coincident epithelial signals restrain commensal-specific CD8αβ+ T cells in the intestine

The paper identifies a commensal-specific CD8αβ+ T cell population in the intestine driven by a single commensal species and shows how epithelial signals regulate their differentiation and restraint.

Hypoxia-inducible factor 2α promotes protective Th2 cell responses during intestinal helminth infection

This study identifies HIF2 as a key regulator of Th2 cell differentiation and function in the small intestine during helminth infection.