Coincident epithelial signals restrain commensal-specific CD8αβ+ T cells in the intestine
Tayla M. Olsen, Matthew J. Dufort, Sheenam Verma, Venkata Krishna Kanth Makani, Benjamin Cameron, Addison R Gralen, Aaron J. Johnson, Alok V. Joglekar, Allyson L. Byrd, Adam Lacy‐Hulbert, Oliver J. Harrison
The paper identifies a commensal-specific CD8αβ+ T cell population in the intestine driven by a single commensal species and shows how epithelial signals regulate their differentiation and restraint.
bioRxiv · May 4, 2026 · PreprintImmunology