Author

Guanhua He

Princeton UniversityORCID 0000-0002-5200-1975Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Martin C. JonikasiD· 2 shared Shan L. HeiD· 2 shared Alejandro Martínez-CalvoiD· 1 shared Alistair J. McCormickiD· 1 shared Angelo Kayser-Browne· 1 shared Antonio Martínez-SáncheziD· 1 shared Ashwani K. Rai· 1 shared Benjamin D. EngeliD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

Martin C. JonikasORCID

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2 papers

Recent·Most cited

Cell BiologyNature Cell BiologyPeer-reviewedMar 17, 2026

Kinase KEY1 controls pyrenoid condensate size throughout the cell cycle by disrupting phase separation interactions

Shan L. He, Linnea Lemma, Alejandro Martínez-Calvo…·Martin C. Jonikas

This study identifies the kinase KEY1 as a regulator of pyrenoid condensate size and dynamics in Chlamydomonas reinhardtii, showing it disrupts phase separation interactions to control condensate dissolution during the cell cycle.

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proteomicsbiophysical modeling

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Molecular BiologyNature PlantsPeer-reviewedNov 23, 2020

The Structural Basis of Rubisco Phase Separation in the Pyrenoid

Shan He, Hui‐Ting Chou, Doreen Matthies…·Martin C. Jonikas

This study identifies the structural basis of Rubisco phase separation in the pyrenoid by analyzing interactions between Rubisco and its linker protein EPYC1 in Chlamydomonas reinhardtii.

148 citationstop 3%

experimental assay

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