Author

Joanna P. Davies

Icahn School of Medicine at Mount SinaiORCID 0000-0002-5206-7667Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

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Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Carisse LansiquotiD· 1 shared H. Ümit KanıskaniD· 1 shared Jian JiniD· 1 shared Michael B. LazarusiD· 1 shared Ruoxi WuiD· 1 shared Xiangyang SongiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

Carisse LansiquotORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintApr 8, 2026

Structural and biochemical characterization of a novel inhibitor of NMNAT1, the gatekeeper of nuclear NAD+ biosynthesis

Carisse Lansiquot, Ruoxi Wu, Joanna P. Davies…·Michael B. Lazarus

The paper identifies AMI-1 as an inhibitor of NMNAT1, shows its effect on NAD+ levels and cancer cell viability, and determines its binding mechanism via cryo-EM.

DOI 10.64898/2026.04.07.716846

structural biologyexperimental assay