Author
Tisch Cancer InstituteORCID 0009-0000-0136-3899Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Sunil Guharajan, Xiangyang Song, Sachi Sengupta…·Sahin Naqvi
The paper introduces dubTAGs, small molecules that stabilize proteins tagged with FKBP12F36V by recruiting deubiquitinases, enabling tunable and reversible control of protein levels.
Qiong Wu, Xiangyang Song, Li Chen…·Jian Jun Jin
The paper identifies a new four-membered-ring chemotype that selectively binds OTUB1, expands its ligandable chemical space, and enables the development of next-generation DUBTACs.
Carisse Lansiquot, Ruoxi Wu, Joanna P. Davies…·Michael B. Lazarus
The paper identifies AMI-1 as an inhibitor of NMNAT1, shows its effect on NAD+ levels and cancer cell viability, and determines its binding mechanism via cryo-EM.