Substrate Stiffness Modulates Fibroblast Extracellular Vesicle Secretion via Mechanotransduction Pathways
Jun Yang, Lara Ece Celebi, Lauren Hawthorne, S. Gulberk Ozcebe, Pınar Zorlutuna
This study shows substrate stiffness affects fibroblast EV size and composition through mechanotransduction pathways, with distinct roles for p53 and thioredoxin in different fibroblast types.
Small · Sep 27, 2025Peer-reviewedBioengineering