T cell-derived IFN-γ Suppresses T Follicular Helper Cell Differentiation and Antibody Responses
Eleonora Sala, Maria Nelli, Chiara Laura, Pietro Di Lucia, Cristian G. Beccaría, Elisa B. Bono, Marta Mangione, Davide Marotta, Valentina Sperto, Marta Grillo, Leonardo Giustini, Francesca Tosi, Jia Nie, Daehong Kim, Giuliana Furiato, , Mirela Kuka
The paper shows that T cell-derived IFN-γ suppresses TFH differentiation and antibody responses by acting through dendritic cells, not directly on CD4+ T cells.
The EMBO Journal · Apr 1, 2025Peer-reviewedImmunology