The activation of mGluR4 rescues parallel fiber LTP, motor learning and social behavior in a mouse model of Fragile X Syndrome
Ricardo Martín, Alberto Samuel Suárez-Pinilla, Nuria García-Font, M. Luisa Laguna-Luque, Juan Carlos López, María Jesús Oset‐Gasque, Agnès Gruart, Jose Maria Delgado-Garcia, Magdalena Torres, José Sánchez‐Prieto
This study shows that activating mGluR4 rescues motor learning and social behavior in Fmr1KO mice by restoring synaptic function and long-term potentiation.
bioRxiv · Apr 29, 2022 · PreprintNeuroscience