Crystal structure of MutYX: A novel clusterless adenine DNA glycosylase with a distinct C-terminal domain and 8-Oxoguanine recognition sphere
Carlos H. Trasviña‐Arenas, Mohammad Hashemian, Melody Malek, Steven Merrill, Andrew J. Fisher, Sheila S. David
The paper determines the crystal structure of MutYX, a clusterless adenine DNA glycosylase, revealing structural adaptations that enable OG recognition without a [4Fe-4S] cofactor.
Nucleic Acids Research · Nov 13, 2025Peer-reviewedBiochemistry