Andrew A. Pitsillides

This paper uses HiP-CT to image the human spine at high resolution, revealing multiscale anatomy and microstructural features without exogenous contrast.

This study shows that microarchitectural features of articular calcified cartilage in mice predict abnormal strain distributions in osteoarthritis.

This paper develops an inversion pipeline using synchrotron tomography and digital volume correlation to estimate elastic properties of rat vertebral endplates, showing high spatial agreement between FEM predictions and experimental data.

This study shows sex differences in osteoblast (OB) extracellular matrix (ECM) composition influence vascular endothelial cell behavior through contact-dependent mechanisms.

This study investigates the regulation and function of trans-physeal growth plate bridges in mice, finding they serve a mechanical role to reduce epiphyseal shear stress during bone growth.

This study uses imaging and modeling to show how structural changes in knee joints predict osteoarthritis onset by altering strain distribution.

This study uses multimodal imaging to examine mechanical strain and microarchitecture in vertebral endplates during intervertebral disc loading, revealing multiscale structural adaptations.

This study uses cryogenic X-ray phase-contrast imaging to analyze cartilage thickness and chondrocyte morphology in mouse joints, revealing differences between osteoarthritis-prone and healthy strains.

This study shows that increased PHOSPHO1 expression in renal osteodystrophy contributes to increased cortical bone mineral density but decreased trabecular bone density.

This study shows that collagen XII deficiency in mice causes patella dislocation and myopathy, with altered gene expression in tenocytes and human patients showing similar patella instability.