Heparan sulfate-function is essential for Integrin-dependent cell-matrix interactions and regulates glycosaminoglycan synthesis synthesis through YAP
Ann-Christine Severmann, Christoph Waterkamp, Meike Buchholz…·Andrea Vortkamp
This study shows that heparan sulfate (HS) is critical for integrin-mediated cell-matrix interactions and regulates glycosaminoglycan (GAG) synthesis through YAP signaling in chondrocytes.