Author

Jianning Kang

Center for Life SciencesORCID 0000-0002-5259-2891Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Research Focus:polygenic risk· 1 Approach:statistical model· 1

Frequent Co-Authors

Aimee S Ramgolam· 1 shared David M. BaileyiD· 1 shared Deepak KhuperkariD· 1 shared Emmanouil MetzakopianiD· 1 shared Flora C. Y. LeeiD· 1 shared Giovanna R. MallucciiD· 1 shared Jernej UleiD· 1 shared Joshua L. FreemaniD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperGenomics

Aimee S Ramgolam

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2 papers

Recent·Most cited

HNRNPH1 regulates the neuroprotective cold-shock protein RBM3 expression through poison exon exclusion

Julie Qiaojin Lin, Deepak Khuperkar, Sofia Pavlou, Stanislaw Makarchuk, Nikolaos Patikas, Flora C. Y. Lee, Julia M. Zbiegly, Jianning Kang, Sarah Frances Field, David M. Bailey, Joshua L. Freeman, Jernej Ule, Emmanouil Metzakopian, Marc‐David Ruepp, Giovanna R. Mallucci

This study identifies HNRNPH1 as a key regulator of RBM3 expression through cold-induced exon skipping, offering potential therapeutic targets for neuroprotection.

The EMBO Journal · May 30, 2023Peer-reviewedMolecular Biology

Functional archaic DNA regulates molecular variation and is associated with disease risk across global populations

Jianning Kang, Aimee S Ramgolam, Louise Le Vot, Robert S. Young

This study identifies functional archaic DNA from Neanderthals and Denisovans that regulates gene expression and disease risk in European and East Asian populations.

bioRxiv · Apr 26, 2023 · PreprintGenomics