Author

Sofia Pavlou

AstraZeneca (United Kingdom)ORCID 0000-0002-1875-4236Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

David Colin BulmeriD· 1 shared David M. BaileyiD· 1 shared Deepak KhuperkariD· 1 shared Emmanouil MetzakopianiD· 1 shared Ewan St. John SmithiD· 1 shared Flora C. Y. LeeiD· 1 shared Fraser WelshiD· 1 shared Giovanna R. MallucciiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

David Colin BulmerORCID

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2 papers

Recent·Most cited

IL-17 sensitises sensory neurons and colonic afferents to noxious stimuli in a PI3K dependent manner

Luke W Paine, James P. Higham, Katie H. Barker, Sofia Pavlou, Fraser Welsh, Ewan St. John Smith, David Colin Bulmer

The paper identifies IL-17's role in enhancing pain sensitivity in the gut via PI3K-dependent mechanisms in ulcerative colitis.

Journal of Neurochemistry · Aug 1, 2025Peer-reviewedNeuroscience

HNRNPH1 regulates the neuroprotective cold-shock protein RBM3 expression through poison exon exclusion

Julie Qiaojin Lin, Deepak Khuperkar, Sofia Pavlou, Stanislaw Makarchuk, Nikolaos Patikas, Flora C. Y. Lee, Julia M. Zbiegly, Jianning Kang, Sarah Frances Field, David M. Bailey, Joshua L. Freeman, Jernej Ule, Emmanouil Metzakopian, Marc‐David Ruepp, Giovanna R. Mallucci

This study identifies HNRNPH1 as a key regulator of RBM3 expression through cold-induced exon skipping, offering potential therapeutic targets for neuroprotection.

The EMBO Journal · May 30, 2023Peer-reviewedMolecular Biology