Yujia Wang

The paper provides per-gene evidence tables from public resources for retrospective gene prioritization, including dates and leakage risk grades for four disease areas.

CaGE alternates guided structure prediction with sequence redesign, fading guidance each cycle, so sequences recover complex catalytic sites unaided; designed nonheme-iron and PLP-dependent enzymes were active.

This paper introduces ABMACT, an agent-based model to simulate tumor-immune dynamics in adoptive cell therapy and identifies key factors for optimal efficacy.

This study identifies immune factor profiles in blood and CSF associated with LRRK2 mutations and Parkinson's disease, showing distinct changes in serum and CSF markers.