Author

Roshni Jaffery

Aligning Science Across Parkinson'sORCID 0000-0003-4128-345XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Ken CheniD· 2 shared Michael A. SchwarzschildiD· 2 shared Weiyi PengiD· 2 shared Xiqun CheniD· 2 shared Ashley M. GuerreroiD· 1 shared Chenggui Xu· 1 shared Fang ZhouiD· 1 shared Hussein A. TawbiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersNeuroscience

Ken ChenORCID

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2 papers

Recent·Most cited

Neurosciencenpj Parkinson s DiseasePeer-reviewedNov 27, 2025

Soluble Immune Factor Profiles in Blood and CSF Associated with LRRK2 Mutations and Parkinson's Disease

Roshni Jaffery, Yuhang Zhao, Sarfraz Ahmed…·Xiqun Chen

This study identifies immune factor profiles in blood and CSF associated with LRRK2 mutations and Parkinson's disease, showing distinct changes in serum and CSF markers.

3 citations

humanproteomics

𝕏 PostBluesky

ImmunologybioRxivPreprintFeb 28, 2024

LRRK2 G2019S mutation suppresses differentiation of Th9 and Treg cells via JAK/STAT3

Ningbo Zheng, Roshni Jaffery, Ashley M. Guerrero…·Weiyi Peng

This study shows that the LRRK2 G2019S mutation impairs Th9 and Treg cell differentiation while enhancing Th2 differentiation through JAK/STAT3 signaling in T cells.

1 citation

mouseproteomics

𝕏 PostBluesky