Alejandra C. Ventura

This study shows that periodic miRNA synthesis can more effectively repress target RNA than constant synthesis, with optimal frequency-dependent repression.

The paper analyzes degeneracy in adaptive circuit mechanisms, showing how it leads to adaptation and resonance in response to different input types.

This study shows that cell signaling systems exhibit transient frequency preference responses during early-stage stimulation, which are absent in periodic regimes and may influence higher-order circuits.

The paper analyzes covalent modification cycles under enzyme-in-excess conditions, showing signal termination and frequency preference responses to periodic inputs.

The paper analyzes how ligand-receptor systems, covalent modification cycles, and transcriptional networks behave before reaching steady-state, showing that they can operate in a PRESS mode.