Author

Arthur Millius

ORCID 0000-0002-5280-6730Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:protein structure· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

A. SherifiD· 1 shared Daron M. StandleyiD· 1 shared Floris J. van EerdeniD· 1 shared Mara Anaís Llamas-CovarrubiasiD· 1 shared Shigenari IshizukaiD· 1 shared Sho YamasakiiD· 1 shared Xiuyuan LuiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

A. SherifORCID

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1 paper

Recent·Most cited

TCR-pMHC complex formation triggers CD3 dynamics

Floris J. van Eerden, A. Sherif, Mara Anaís Llamas-Covarrubias, Arthur Millius, Xiuyuan Lu, Shigenari Ishizuka, Sho Yamasaki, Daron M. Standley

This study identifies an allosteric mechanism where TCR-pMHC binding induces CD3 dynamics through conformational changes, with the TCRβ FG loop acting as a gatekeeper and the connecting peptide as a hinge.

bioRxiv · Jul 27, 2022 · PreprintMolecular Biology