Author

Sho Yamasaki

Immunology Frontier Research Center, The University of OsakaORCID 0000-0002-5184-6917Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1 Cell Biology· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:CITE-seq· 1

Frequent Co-Authors

Xiuyuan LuiD· 3 shared Daron M. StandleyiD· 2 shared Mara Anaís Llamas-CovarrubiasiD· 2 shared A. SherifiD· 1 shared Alison J. HobroiD· 1 shared Anthony Wayne PurcelliD· 1 shared Arthur MilliusiD· 1 shared Barbora Salcman· 1 shared

Activity by Year

2022-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersImmunology

Xiuyuan LuORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A lipid-driven, microbe-independent mechanism of acne via Lrig1+ follicular progenitor cells

Takashi Sugihira, Masakazu Tamai, Kohei Takagi, Barbora Salcman, Tetsuro Kobayashi, Alison J. Hobro, Seitaro Nakagawa, Yukiko Takeuchi, Eri Ishikawa, Motoko Maekawa, Yuji Owada, Naohiro Inohara, Hiroki Takahashi, Nicholas Isaac Smith, Sho Yamasaki, , Yuumi Nakamura

This study identifies C16:0 as a lipid driver of acne through Lrig1+ follicular progenitor cells, independent of microbes.

bioRxiv · Aug 30, 2025 · PreprintCell Biology

The antigen presenting molecule MR1 binds riboflavin catabolites

Mohamed R. Abdelaal, Jieru Deng, Mitchell P. McInerney, Emi Ito, Anthony Wayne Purcell, Sho Yamasaki, Jóse A. Villadangos, Hamish E. G. McWilliam, Nicholas A. Gherardin, Jamie Rossjohn, Wael Awad

This study identifies riboflavin catabolites that bind MR1, reduce its cell surface expression, and inhibit MAIT cell activation.

bioRxiv · Jul 20, 2025 · PreprintBiochemistry

The presenting HLA determines fidelity of SARS-CoV-2 spike protein epitope prediction

Charles R. Schutt, Deren Birol, Xiuyuan Lu, Sho Yamasaki

The paper compares epitope prediction methods across different HLA types and finds that prediction accuracy varies with HLA, suggesting broader HLA coverage improves epitope identification.

Vaccine · Jun 12, 2025Peer-reviewedImmunology

InterClone: Store, Search and Cluster Adaptive Immune Receptor Repertoires

Jan Wilamowski, Zichang Xu, Hendra Saputra Ismanto, Songling Li, Shunsuke Teraguchi, Mara Anaís Llamas-Covarrubias, Xiuyuan Lu, Sho Yamasaki, Daron M. Standley

InterClone stores, searches, and clusters adaptive immune receptor repertoires, demonstrating its utility in analyzing SARS-CoV-2 antibodies and TCRs from different donor groups.

bioRxiv · Jul 31, 2022 · PreprintBioinformatics

TCR-pMHC complex formation triggers CD3 dynamics

Floris J. van Eerden, A. Sherif, Mara Anaís Llamas-Covarrubias, Arthur Millius, Xiuyuan Lu, Shigenari Ishizuka, Sho Yamasaki, Daron M. Standley

This study identifies an allosteric mechanism where TCR-pMHC binding induces CD3 dynamics through conformational changes, with the TCRβ FG loop acting as a gatekeeper and the connecting peptide as a hinge.

bioRxiv · Jul 27, 2022 · PreprintMolecular Biology