An atlas of TF driven gene programs across human cells
J. Patrick Pett, Martin Prete, Duy Pham, Nick England, Hao Yuan, Elena Prigmore, Elizabeth J. Tuck, Ágnes Oszlánczi, Ken To, Chuan Xu, Chenqu Suo, Emma Dann, Peng He, Veronika R. Kedlian, Kazumasa Kanemaru, , Kerstin B. Meyer
The paper creates a regulon atlas mapping TF activity across human cell types and uses it to link disease signatures to cell types and TFs, improving disease risk locus analysis.
bioRxiv · May 30, 2025 · PreprintGenetics