Lingfei Luo

A tunnel microtract organ for T cell progenitor homing is formed by neural crest morphogenesis via Sox10-Cdc42 axis

The paper identifies a tunnel microtract (TMT) as a neural crest-derived organ essential for T cell progenitor homing, showing Sox10-Cdc42 signaling drives its formation in zebrafish and mice.

Endothelial Brg1 fine-tunes Notch signaling during zebrafish heart regeneration

This study shows that endothelial Brg1 regulates Notch signaling in zebrafish heart regeneration by modulating H3K4me3 levels and interacting with Kdm7aa.

Urgent Brain Vascular Regeneration Occurs via Lymphatic Transdifferentiation

This study shows that urgent brain vascular regeneration after ischemic stroke occurs through lymphatic transdifferentiation, mediated by EphrinB2a/EphB4a/Notch signaling in zebrafish.

Cerebrovascular Injuries Induce Lymphatic Invasion into Brain Parenchyma to Guide Vascular Regeneration in Zebrafish

This study shows that cerebrovascular injuries in zebrafish trigger lymphatic invasion into brain parenchyma, which helps resolve edema and guides vascular regeneration.

The effector of Hippo signaling, Taz, is required for formation of the micropyle and fertilization in zebrafish

This study identifies Taz as essential for micropyle formation and fertilization in zebrafish by showing that Taz mutants lack micropyles and are infertile.

Zebrafish hhex null mutant develops an intrahepatic intestinal tube due to de-repression of cdx1b and pdx1

This study shows that zebrafish hhex-null mutants develop an intrahepatic intestinal tube due to de-repression of cdx1b and pdx1, which replaces the normal hepatopancreatic duct system.