Author

Saygin Gulec

University of North Carolina at Chapel HillORCID 0000-0002-5326-5550Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Aarav MehtaiD· 2 shared Christina Ford· 2 shared Elizabeth BrunkiD· 2 shared Jingting CheniD· 2 shared Santiago HaaseiD· 2 shared Yue WangiD· 2 shared Alison M. Rojas· 1 shared Caroline A Tomblin· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersGenomics

Aarav MehtaORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintApr 26, 2025

Extrachromosomal DNA Gives Cancer a New Evolutionary Pathway

Yue Wang, Oliver Cope, Jingting Chen…·Elizabeth Brunk

The paper shows that ecDNA allows tumors to adapt rapidly by maintaining a spectrum of gene expression levels across cells, rather than relying on clonal expansion.

2 citations

humanmultiome

GenomicsbioRxivPreprintDec 18, 2023

CytoCellDB: A Resource Database For Classification and Analysis of Extrachromosomal DNA in Cancer

Jacob Fessler, Stephanie Ting, Hong Yi…·Elizabeth Brunk

CytoCellDB is a database that expands the number of cancer cell lines with ecDNA annotations, enabling analysis of ecDNA in relation to molecular data and drug responses.

1 citation

humanproteomics