Large-scale conformational analysis explains G-quadruplex topological landscape
Michał Jurkowski, Mateusz Kogut, Michał Olewniczak, Jan Glinko, Jacek Czub
The paper analyzes G-quadruplex conformational landscapes by evaluating 20,000 unique structures from 128 DNA sequences, revealing that long-distance propeller loops restrict folding and are influenced by G4 helicity.
The Journal of Physical Chemistry B · Sep 11, 2025Peer-reviewedBioinformatics