Yihui Cen

scDesignPop generates realistic population-scale single-cell RNA-seq for power analysis, benchmarking, and privacy protection

scDesignPop generates realistic population-scale scRNA-seq data for power analysis, benchmarking, and privacy protection by simulating genetic effects and cell-type-specific eQTLs.

scCDC: a computational method for gene-specific contamination detection and correction in single-cell and single-nucleus RNA-seq data

scCDC detects and corrects contamination in scRNA-seq and snRNA-seq data by identifying contamination-causing genes, achieving better accuracy than existing methods.