Ying Xiao

scSAID provides a cross-species single-cell skin atlas to study psoriasis, revealing species-specific molecular signatures and identifying a novel drug target.

This study shows that reducing Top2b extends lifespan and healthspan in multiple species by altering the epigenetic landscape and reversing aging hallmarks.

scCDC detects and corrects contamination in scRNA-seq and snRNA-seq data by identifying contamination-causing genes, achieving better accuracy than existing methods.