Wanlu Liu

The paper shows that TCR germline sequences encode MHC restriction, revealing a structural basis for TCR recognition of MHC molecules independent of antigenic peptide.

The paper characterizes RNA profiles in P-bodies of human embryonic stem cells and mesodermal cells, revealing cell type-specific RNA composition and roles in differentiation.

The paper constructs a single-cell GEX-TCR reference atlas and introduces TCR-DeepInsight, a deep-learning framework to characterize disease-associated TCRs.

The paper benchmarks TCR reconstruction methods from scRNA-seq data, finding TRUST4 performs best, while sequencing depth limits accuracy.

scCDC detects and corrects contamination in scRNA-seq and snRNA-seq data by identifying contamination-causing genes, achieving better accuracy than existing methods.

This study benchmarks eleven isoform detection methods for TGS data, finding StringTie2 and Bambu excel in sensitivity and precision, respectively.

The paper creates a cell atlas of early human peri-implantation lineages and develops an embryo-like assembloid to study lineage development and signaling mechanisms.

MSdb provides an integrated expression atlas of human musculoskeletal system data with visualization, analysis tools, and curated phenotype information.

RAD identifies region-associated differentially expressed genes by linking genomic regions to gene expression changes, providing visualization and statistical analysis.

The paper identifies MBD9 as an interacting protein of the Arabidopsis SWR1-C complex required for H2A.Z deposition at specific gene loci.