Human SerRS/SIRT2 complex structure reveals cross regulation between translation and NAD+ metabolism
Qian Zhang, Huimin Zhang, Marscha Hirschi, Sheng Li, Gabriel C. Lander, Yang Jie, Xiang‐Lei Yang
The paper reveals a cross-regulation between translation and NAD+ metabolism through the interaction of SerRS and SIRT2, mediated by ADP-ribose.
bioRxiv · Sep 23, 2025 · PreprintMolecular Biology