NeurosciencebioRxivPreprint
Targeting eIF2α in TBI-induced traumatic optic neuropathy: Effects of Salubrinal and the Integrated Stress Response Inhibitor.
Shelby M. Hetzer, Rohan Bellary, Jordyn N. Torrens…·Nathan K. Evanson
This study investigates the effects of Salubrinal and ISRIB on eIF2 phosphorylation in TBI-induced traumatic optic neuropathy, finding that both drugs impair visual function in control animals and show limited benefit in injured mice.
DOI 10.1101/2024.02.15.580435