Brigid Sweeney Boland

This paper identifies two stromal states in IBD that predict clinical outcomes and shows that targeting one state can reverse disease pathology.

The paper investigates how spatial location influences the functional diversity of memory CD8 T cells by analyzing their transcriptomes in the small intestine.

F.O.R.W.A.R.D is a network-based target prioritization framework that uses clinical outcomes and transcriptomic data to predict drug efficacy in IBD, achieving 100% predictive accuracy in benchmarking.

This paper expands the interpretability of human metabolomes by using food-based annotations, increasing the fraction of molecular features understood 7-fold.