Author

Harrison M. Penrose

University of California San DiegoORCID 0000-0001-7957-5066Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Brigid Sweeney BolandiD· 2 shared Courtney TindleiD· 2 shared Ella McLareniD· 2 shared Madhubanti MullickiD· 2 shared Pradipta GhoshiD· 2 shared Saptarshi SinhaiD· 2 shared Chia-Chian Hsieh· 1 shared Gajanan Dattatray KatkariD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPhysiology

Brigid Sweeney BolandORCID

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintJun 13, 2026

A stromal-state dichotomy governs recalcitrance or remission in inflammatory bowel disease

Courtney Tindle, Harrison M. Penrose, Saptarshi Sinha…·Pradipta Ghosh

This paper identifies two stromal states in IBD that predict clinical outcomes and shows that targeting one state can reverse disease pathology.

DOI 10.64898/2026.05.01.720931

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsbioRxivPreprintJul 16, 2024

F.O.R.W.A.R.D: A Data-Driven Framework for Network-Based Target Prioritization in Drug Discovery

Saptarshi Sinha, Ella McLaren, Madhubanti Mullick…·Pradipta Ghosh

F.O.R.W.A.R.D is a network-based target prioritization framework that uses clinical outcomes and transcriptomic data to predict drug efficacy in IBD, achieving 100% predictive accuracy in benchmarking.

6 citations

humanbulk RNA-seq

𝕏 PostBluesky