Lee Cossell

The paper develops open-source Python tools for accurately mapping the location of dye-labelled probes and fluorescent cells in whole-brain microscopy images.

The paper introduces a deep learning algorithm for automated 3D detection of neuronal somata in whole mouse brain images, demonstrating its effectiveness on fluorescently labeled cell populations.

The paper quantifies the similarity in long-range presynaptic connectivity between excitatory and inhibitory L2/3 neurons in mouse V1, finding they receive input from similar brain regions in comparable proportions.

This study shows that visual input modifies intrinsic excitability of visual cortical neurons in mice, compensating for changes in synaptic drive to maintain sensory function.