C. Henrique Serezani

This study shows that oleic acid reduces NLRP3 inflammasome activity in macrophages, preventing their death and limiting psoriasis-like skin inflammation in mice.

This study uses transcriptomic profiling to identify metabolic, inflammatory, and oxidative stress pathways in diabetic porcine wound healing, supporting the model for therapeutic testing.

This study shows that miR-21 inhibition improves bacterial clearance and reduces inflammation in S. aureus skin infections by modulating MyD88-dependent pathways.

The paper establishes a murine dermal macrophage cell line, SB89, which maintains key functional and transcriptional features of resident dermal macrophages and offers a renewable model for skin immunology research.

This study shows hyperglycemia impairs skin antifungal defenses by promoting maladaptive Dectin-1 signaling, which can be mitigated by GLP-1 agonists.