Author

Helena de Puig

Harvard UniversityORCID 0000-0002-5368-6996Unclaimed ORCID profile · follow to get notified of new preprints

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Synthetic Biology· 1

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Approach:experimental assay· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

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Allison Flores· 1 shared Carmen Escobedo‐LuceaiD· 1 shared Dinara SayfullinaiD· 1 shared Erkin KuruiD· 1 shared George McDonald ChurchiD· 1 shared James J. CollinsiD· 1 shared Michaël MoretiD· 1 shared Subhrajit Rout· 1 shared

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2026-2026 · peak 1/yr

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Allison Flores

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Recent·Most cited

Synthetic BiologybioRxivPreprintMay 16, 2026

Genetic code expansion enables programmable covalent protein design

Helena de Puig, Erkin Kuru, Michaël Moret…·George McDonald Church

This paper introduces AminoX, a platform for programmable covalent protein design using non-standard amino acids, enabling efficient screening and functional validation of covalent warheads and multifunctional proteins.

DOI 10.64898/2026.05.15.725538

protein sequenceexperimental assay

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