Author

Jingyi Hu

Cornell UniversityORCID 0000-0002-5385-9113Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 1 Approach:comparative / phylogenetic analysis· 1 Assay:DNA methylation· 1

Frequent Co-Authors

J. Brooks CrickardiD· 3 shared Amanda Xu· 1 shared Bryan Ferlez· 1 shared David A. MoragaiD· 1 shared Ilayda KorkmaziD· 1 shared James T. InmaniD· 1 shared Jin QianiD· 1 shared Lauren Peysakhova· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiochemistry

J. Brooks CrickardORCID

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3 papers

Recent·Most cited

Rad54 separation of function mutation highlights unique roles during homologous recombination

Jingyi Hu, David A. Moraga, Amanda Xu, Lauren Peysakhova, J. Brooks Crickard

This study identifies a Rad54 mutation that separates its function during homologous recombination, revealing a novel intermediate essential for stabilizing D-loop structures.

bioRxiv · Oct 15, 2025 · PreprintBiochemistry

The Eukaryotic homology search complex distorts donor DNA structure to probe for homology

Mitchell V Woodhouse, Jingyi Hu, Meiling Wu, Jin Qian, James T. Inman, Michelle Dong Wang, J. Brooks Crickard

This study investigates how Rad51 and Rad54 remodel donor DNA during homology search by applying tension and torsion forces, revealing their role in controlling Rad51-ssDNA filament dynamics.

bioRxiv · Aug 28, 2025Biochemistry

Evolutionary specialization of Rad51 and Dmc1 tune recombination outcomes

Bryan Ferlez, P.C. Huang, Jingyi Hu, Ilayda Korkmaz, J. Brooks Crickard

This study identifies evolutionary changes in Rad51 and Dmc1 that influence recombination outcomes by altering DNA binding properties and pathway stability.

bioRxiv · Feb 19, 2025 · PreprintEvolutionary Biology