Author

David A. Moraga

Cornell UniversityORCID 0000-0003-1504-9109Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Amanda Xu· 1 shared Anthony Q. BuiiD· 1 shared Christopher J. HosfordiD· 1 shared Emerson Ricardo SantiagoiD· 1 shared J. Brooks CrickardiD· 1 shared Jingyi HuiD· 1 shared Joshua S. ChappieiD· 1 shared Lauren Peysakhova· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Amanda Xu

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 1, 2026

Structural characterization the LlaI anti-phage defense system reveals insights into the evolution of nucleotide specificity and the organization of DNA binding in McrBC restriction complexes

Anthony Q. Bui, Christopher J. Hosford, Yiming Niu…·Joshua S. Chappie

The paper reports crystal structures of LlaI components, revealing nucleotide specificity evolution and DNA binding mechanisms in McrBC restriction complexes.

DOI 10.64898/2026.08.31.748284

bacteria (other)structural biology

𝕏 PostBluesky

BiochemistrybioRxivPreprintOct 15, 2025

Rad54 separation of function mutation highlights unique roles during homologous recombination

Jingyi Hu, David A. Moraga, Amanda Xu…·J. Brooks Crickard

This study identifies a Rad54 mutation that separates its function during homologous recombination, revealing a novel intermediate essential for stabilizing D-loop structures.

DOI 10.1101/2025.10.15.682645

experimental assaycell signaling & trafficking

𝕏 PostBluesky