Author

Meiling Wu

Howard Hughes Medical InstituteORCID 0000-0001-8827-2999Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Organism:human· 1

Frequent Co-Authors

James T. InmaniD· 2 shared Michelle Dong WangiD· 2 shared Mitchell V WoodhouseiD· 2 shared Curtis BeckiD· 1 shared J. Brooks CrickardiD· 1 shared James M. BergeriD· 1 shared Jin QianiD· 1 shared Jingyi HuiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

James T. InmanORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivAug 28, 2025

The Eukaryotic homology search complex distorts donor DNA structure to probe for homology

Mitchell V Woodhouse, Jingyi Hu, Meiling Wu…·J. Brooks Crickard

This study investigates how Rad51 and Rad54 remodel donor DNA during homology search by applying tension and torsion forces, revealing their role in controlling Rad51-ssDNA filament dynamics.

2 citations

DNA methylationexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintOct 15, 2024

Human Topoisomerase IIα Promotes Chromatin Condensation Via a Phase Transition

Meiling Wu, Curtis Beck, Joyce H. Lee…·Michelle Dong Wang

This study identifies a new role for human topoisomerase IIα in promoting chromatin condensation through a polymer-collapse phase transition, independent of its catalytic activity.

10 citations

humanDNA methylation

𝕏 PostBluesky