BioinformaticsbioRxivPreprint
Unexpected variability of allelic imbalance estimates from RNA sequencing
Asia Mendelevich, S.V. Vinogradova, Saumya Gupta…·Alexander A. Gimelbrant
The paper assesses allelic imbalance variability in RNA sequencing and finds technical replicates show up to 7-fold higher variation than expected, which can be mitigated to improve differential analysis.
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