Asia Mendelevich

This paper introduces MPATH, a method to temporally order epigenetic modifications using long-read sequencing, revealing sub-cell-cycle dynamics of methylation states and nucleosome occupancy.

The paper introduces a spike-in method to improve allele-specific expression analysis by reducing technical noise and cost.

The paper identifies DNA methylation as a key mechanism for maintaining monoallelic expression on autosomes and reveals its tunable control of allele-specific expression.

The paper assesses allelic imbalance variability in RNA sequencing and finds technical replicates show up to 7-fold higher variation than expected, which can be mitigated to improve differential analysis.