Author

Hongru Li

Icahn School of Medicine at Mount SinaiORCID 0000-0002-5422-2341Unclaimed ORCID profile · follow to get notified of new preprints

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Hongru Li1 paper

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam R. RootiD· 1 shared Alan LeungiD· 1 shared Alex H. Ramos· 1 shared Amarendra PeguiD· 1 shared Anne M. JecroisiD· 1 shared Benjamin K. CheniD· 1 shared Brett T. HanniganiD· 1 shared Claudio L. Morales-Pérez· 1 shared

Activity by Year

2025-2026 · peak 1/yr

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10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

Adam R. RootORCID

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2 papers

Recent·Most cited

MicrobiologyJournal of VirologyPeer-reviewedMay 28, 2026

Endocytic motif on HIV Env regulates cleavage status and antibody neutralization of cell-free and cell-to-cell infection

Dania M. Figueroa, Tony R. Valencia, Hongru Li, Benjamin K. Chen

This study shows that HIV Env endocytosis affects cleavage status and antibody neutralization, with uncleaved Env increasing sensitivity to certain antibodies in cell-to-cell infection.

1 citation

humanproteomics

MicrobiologybioRxivPreprintMar 30, 2025

Functional and structural characterization of a combination of pan-sarbecovirus antibodies with potent antiviral activity

Grace Marden, Kimberly P. Schmitt, Maxwell I. Zimmerman…·Francesco Borriello

This study identifies two broadly neutralizing sarbecovirus antibodies that resist viral evolution and show improved neutralization when combined.

2 citations

deep learningdrug response / drug discovery