Author

Christina D. Smolke

Chan Zuckerberg Biohub San FranciscoORCID 0000-0002-5449-8495Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Christina D. Smolke2 papers

Biology Disciplines

Click to filter author papers

Synthetic Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein design· 1 Approach:statistical model· 1 Organism:yeast· 1

Frequent Co-Authors

Brent TownshendiD· 1 shared Deze KongiD· 1 shared Matias KaplaniD· 1 shared Shireen S. RudinaiD· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 1 mutual co-author link

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperSynthetic Biology

Brent TownshendORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Highly Multiplexed Selection of RNA Aptamers Against a Small Molecule Library

Brent Townshend, Matias Kaplan, Christina D. Smolke

The paper describes a method to select RNA aptamers against a large small molecule library, identifying biosensors with high sensitivity and diverse sensing patterns.

PLoS ONE · Sep 15, 2022Peer-reviewedSynthetic Biology

Building an RNA switch-based selection system for enzyme evolution in yeast

Deze Kong, Christina D. Smolke

The paper develops an RNA switch-based selection system in yeast to enable enzyme evolution by linking compound production to selection gene expression.

bioRxiv · Jun 14, 2022 · PreprintSynthetic Biology

A Novel Chromatin-Opening Element for Stable Long-term Transgene Expression

Shireen S. Rudina, Christina D. Smolke

The paper identifies a novel UCOE, SRF-UCOE, that improves transgene stability in mammalian cells by resisting DNA methylation and histone deacetylation compared to existing UCOEs.

bioRxiv · May 3, 2019 · PreprintSynthetic Biology