Athanasios Papangelis

The paper evaluates the crosslinking efficiency of bifunctional diazirine lipid probes using STARD10 and mass spectrometry, finding that only 5% form covalent protein-lipid crosslinks.

This study identifies GPRC6A as a key regulator of mTORC1 signaling and tau pathology in tauopathies, showing that targeting GPRC6A could reduce tau accumulation and related neurodegeneration.