H. Mathilda Lennartz

This study quantifies lipid sorting during clathrin-mediated endocytosis and finds that lipid asymmetry in the plasma membrane explains observed partitioning, with minimal selectivity for cytoplasmic leaflet lipids compared to non-vesicular trafficking.

The paper identifies lipid specificity in membrane organizing protein complexes by mapping lipid-protein interactions and demonstrating phosphatidylethanolamine's role in stabilizing NDC1 and MIC60.

The paper evaluates the crosslinking efficiency of bifunctional diazirine lipid probes using STARD10 and mass spectrometry, finding that only 5% form covalent protein-lipid crosslinks.

The paper introduces bifunctional ether lipid probes to study intracellular transport kinetics and identifies differences in transport rates between alkyl- and vinyl-linked ether lipids.

The paper quantifies lipid transport between organelles in mammalian cells, revealing non-vesicular transport as a key mechanism for species-specific lipid sorting.

This study shows that disrupting plasma membrane lipid asymmetry in mammalian cells alters cellular energetics by shifting metabolism from anabolic to catabolic states.

This paper introduces a correlative light and electron microscopy workflow to quantify lipid densities in membrane nanodomains and finds sphingomyelin partitions into specific endosomal structures.