Cancer BiologyPLoS BiologyPeer-reviewed
PRMT5-mediated histone methylation regulates alternative splicing via MECP2-PTBP1 to promote EMT in breast cancer hypoxia
Srinivas Abhishek Mutnuru, Pooja Yadav, Parik Kakani…·Sanjeev Shukla
7 citations
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Indian Institute of Science Education and Research, BhopalORCID 0000-0002-5460-7655Unclaimed ORCID profile · follow to get notified of new preprints
2 papers
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Srinivas Abhishek Mutnuru, Pooja Yadav, Parik Kakani…·Sanjeev Shukla
Parik Kakani, Shruti Ganesh Dhamdhere, Deepak Pant…·Sanjeev Shukla
This study shows hypoxia-induced CTCF promotes EMT in breast cancer by regulating alternative splicing through chromatin looping and RNA Pol II pausing.