Author

Deepak Pant

Indian Institute of Science Education and Research, BhopalORCID 0000-0002-7925-9394Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Parik KakaniiD· 2 shared Rushikesh Joshi· 2 shared Sanjeev ShuklaiD· 2 shared Aaron A. SmargoniD· 1 shared Abin Sabu· 1 shared Anchala PandeyiD· 1 shared Atul Samaiya· 1 shared Christian R. FagreiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

Parik KakaniORCID

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3 papers

Recent·Most cited

Small nuclear RNAs enhance protein-free RNA-programmable base conversion on mammalian coding transcripts

Aaron A. Smargon, Deepak Pant, Trent A. Gomberg, Christian R. Fagre, Sofia Glynne, Johnathan Nguyen, Jack T. Naritomi, Wendy V. Gilbert, Gene Wei-Ming Yeo

This study shows that guided A>I snRNAs improve RNA base conversion efficiency and reduce off-target effects compared to ADAR-recruiting circular RNAs in human cells.

Nature Chemical Biology · Sep 18, 2025Peer-reviewedBiochemistry

Interplay of YEATS2 and GCDH regulates histone crotonylation and drives EMT in head and neck cancer

Deepak Pant, Parik Kakani, Rushikesh Joshi, Abin Sabu, Shruti Agrawal, Atul Samaiya, Sanjeev Shukla

This study identifies a novel mechanism where YEATS2 and GCDH regulate histone crotonylation, promoting EMT in head and neck cancer.

eLife · Aug 14, 2025Peer-reviewedCancer Biology

Hypoxia-induced CTCF mediates alternative splicing via coupling chromatin looping and RNA Pol II pause to promote EMT in breast cancer

Parik Kakani, Shruti Ganesh Dhamdhere, Deepak Pant, Rushikesh Joshi, Sachin Mishra, Anchala Pandey, Dimple Notani, Sanjeev Shukla

This study shows hypoxia-induced CTCF promotes EMT in breast cancer by regulating alternative splicing through chromatin looping and RNA Pol II pausing.

Cell Reports · Feb 1, 2025Peer-reviewedMolecular Biology