In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19
Isabelle Q. Phan, Sandhya Subramanian, David E. Kim, Michael Murphy, Deleah Pettie, Lauren P. Carter, Ivan V. Anishchenko, Lynn K. Barrett, Justin K. Craig, Logan M. Tillery, Roger Shek, Whitney E. Harrington, David M. Koelle, Anna Wald, David Veesler, , Wesley C. Van Voorhis A
The paper predicts SARS-CoV-2 B-cell epitopes using computational methods and validates them with ELISA, finding two antigens with high sensitivity and specificity for serological diagnosis of COVID-19.
Scientific Reports · Feb 22, 2021Peer-reviewedBioinformatics