Wesley C. Van Voorhis A

This paper reports the purification, crystallization, and structure of Trichomonas vaginalis pyrophosphate-dependent phosphofructokinase (TvPPi-PFK), revealing its active site and additional ligand-binding sites.

This study shows that BKI-1708 induces baryzoite formation in T. gondii, N. caninum, and B. besnoiti, which exhibit distinct phenotypic and proteomic features and lack complete cytokinesis.

This study identifies four deleterious mutations in SARS-CoV-2 Omicron variants that affect the conformational stability and dynamics of the Spike protein's RBD and S2 subunit.

The paper reports the structural determination of 19 N. fowleri proteins, identifying potential drug targets with structural differences from human homologs.

The paper predicts SARS-CoV-2 B-cell epitopes using computational methods and validates them with ELISA, finding two antigens with high sensitivity and specificity for serological diagnosis of COVID-19.

The paper identifies 59 compounds that inhibit Balamuthia mandrillaris growth and reconstructs its transcriptome to determine potential molecular targets for drug development.